Publications

    2019

  • Hamy, Anne-Sophie; Darrigues, Lauren; Laas, Enora; Croze, Diane De; Topciu, Lucian; Lam, Giang-Thanh; Evrevin, Clemence; Rozette, Sonia; Laot, Lucie; Lerebours, Florence; Pierga, Jean-Yves; Osdoit, Marie; Faron, Matthieu; Feron, Jean-Guillaume; Lae, Marick; Reyal, Fabien, 2019, "Prognostic value of the Residual Cancer Burden index according to breast cancer subtype: validation on a cohort of BC patients treated by neoadjuvant chemotherapy.", medRxiv, DOI:10.1101/19008896

  • Brandao, Mariana; Reyal, Fabien; Hamy, Anne-Sophie; Piccart-Gebhart, Martine, 2019, "Neoadjuvant treatment for intermediate/high-risk HER2-positive and triple-negative breast cancers: no longer an 'option' but an ethical obligation", ESMO open, vol. 4, no. 3, pp. e000515 DOI:10.1136/esmoopen-2019-000515

  • Labrosse, Julie; Lam, Thanh; Sebbag, Clara; Benque, Milena; Abdennebi, Ines; Merckelbagh, Hilde; Osdoit, Marie; Priour, Mael; Guerin, Julien; Balezeau, Thomas; Grandal, Beatriz; Coussy, Florence; Bobrie, Angelique; Ferrer, Loic; Laas, Enora; Feron, Jean-Guillaume; Reyal, Fabien; Hamy, Anne-Sophie, 2019, "Text Mining in Electronic Medical Records Enables Quick and Efficient Identification of Pregnancy Cases Occurring After Breast Cancer", JCO clinical cancer informatics, DOI:10.1200/CCI.19.00031

  • Hamy, Anne-Sophie; Derosa, Lisa; Valdelievre, Constance; Yonekura, Satoru; Opolon, Paule; Priour, Mael; Guerin, Julien; Pierga, Jean-Yves; Asselain, Bernard; Croze, Diane De; Pinheiro, Alice; Lae, Marick; Talagrand, Laure-Sophie; Laas, Enora; Darrigues, Lauren; Grandal, Beatriz; Marangoni, Elisabetta; Montaudon, Elodie; Kroemer, Guido; Zitvogel, Laurence; Reyal, Fabien, 2019, "Comedications influence immune infiltration and pathological response to neoadjuvant chemotherapy in breast cancer", OncoImmunology, vol. 0, no. 0, pp. 1677427 DOI:10.1080/2162402X.2019.1677427

  • Abecassis, Judith; Reyal, Fabien; Vert, Jean-Philippe, 2019, "CloneSig: Joint inference of intra-tumor heterogeneity and signature deconvolution in tumor bulk sequencing data", bioRxiv, DOI:10.1101/825778

  • Abecassis, Judith; Hamy, Anne-Sophie; Laurent, Cecile; Sadacca, Benjamin; Bonsang-Kitzis, Helene; Reyal, Fabien; Vert, Jean-Philippe, 2019, "Assessing reliability of intra-tumor heterogeneity estimates from single sample whole exome sequencing data", PLOS ONE, vol. 14, no. 11, pp. e0224143 DOI:10.1371/journal.pone.0224143

  • Hamy, Anne-Sophie; Tury, Sandrine; Wang, Xiaofei; Gao, Junheng; Pierga, Jean-Yves; Giacchetti, Sylvie; Brain, Etienne; Pistilli, Barbara; Marty, Michel; Espie, Marc; Benchimol, Gabriel; Laas, Enora; Lae, Marick; Asselain, Bernard; Aouchiche, Brice; Edelman, Martin; Reyal, Fabien, 2019, "Celecoxib With Neoadjuvant Chemotherapy for Breast Cancer Might Worsen Outcomes Differentially by COX-2 Expression and ER Status: Exploratory Analysis of the REMAGUS02 Trial", Journal of Clinical Oncology, vol. 37, no. 8, pp. 624-635 DOI:10.1200/JCO.18.00636

  • Faucheux, L.; Grandclaudon, M.; Perrot-Dockes, M.; Sirven, P.; Berger, F.; Hamy, A.S.; Fourchotte, V.; Vincent-Salomon, A.; Mechta-Grigoriou, F.; Reyal, F.; Scholer-Dahirel, A.; Guillot-Delost, M.; Soumelis, V., 2019, "A multivariate Th17 metagene for prognostic stratification in T cell non-inflamed triple negative breast cancer", Oncoimmunology, DOI:10.1080/2162402X.2019.1624130

  • Laas, Enora; Hamy, Anne-Sophie; Michel, Anne-Sophie; Panchbhaya, Nabilah; Faron, Matthieu; Lam, Thanh; Carrez, Sophie; Pierga, Jean-Yves; Rouzier, Roman; Lerebours, Florence; Feron, Jean-Guillaume; Reyal, Fabien, 2019, "Impact of time to local recurrence on the occurrence of metastasis in breast cancer patients treated with neoadjuvant chemotherapy: A random forest survival approach", PLoS ONE, DOI:10.1371/journal.pone.0208807

  • Naylor, P.; Lae, M.; Reyal, F.; Walter, T., 2019, "Segmentation of Nuclei in Histopathology Images by Deep Regression of the Distance Map", IEEE Transactions on Medical Imaging, vol. 38, no. 2, pp. 448-459 DOI:10.1109/TMI.2018.2865709

  • Brandao, M; Reyal, F.; Hamy, AS; Piccart, M, 2019, "Neoadjuvant treatment for intermediate/high-risk HER2-positive and triple-negative breast cancers: no longer an "option" but an ethical obligation.", ESMO open, DOI:

  • Hamy, Anne-Sophie; Bonsang-Kitzis, Helene; Croze, Diane De; Laas, Enora; Darrigues, Lauren; Topciu, Lucian; Menet, Emmanuelle; Vincent-Salomon, Anne; Lerebours, Florence; Pierga, Jean-Yves; Brain, Etienne; Feron, Jean-Guillaume; Benchimol, Gabriel; Lam, Giang-Thanh; Lae, Marick; Reyal, Fabien, 2019, "Interaction between molecular subtypes, stromal immune infiltration before and after treatment in breast cancer patients treated with neoadjuvant chemotherapy", Clinical Cancer Research, DOI:10.1158/1078-0432.CCR-18-3017

    • 2018

  • Marangoni, Elisabetta; Laurent, Cecile; Coussy, Florence; El-Botty, Rania; Chateau-Joubert, Sophie; Servely, Jean-Luc; de Plater, Ludmilla; Assayag, Franck; Dahmani, Ahmed; Montaudon, Elodie; Nemati, Fariba; Fleury, Justine; Vacher, Sophie; Gentien, David; Rapinat, Audrey; Foidart, Pierre; Sounni, Nor Eddine; Noel, Agnes; Vincent-Salomon, Anne; Lae, Marick; Decaudin, Didier; Roman-Roman, Sergio; Bieche, Ivan; Piccart, Martine; Reyal, Fabien, 2018, "Capecitabine Efficacy Is Correlated with TYMP and RB1 Expression in PDX Established from Triple-Negative Breast Cancers", Clinical Cancer Research: An Official Journal of the American Association for Cancer Research, vol. 24, no. 11, pp. 2605-2615 DOI:10.1158/1078-0432.CCR-17-3490

  • Cremoux, Patricia De; Hamy, Anne-Sophie; Lehmann-Che, Jacqueline; Scott, Veronique; Sigal, Brigitte; Mathieu, Marie-Christine; Bertheau, Philippe; Guinebretiere, Jean Marc; Pierga, Jean Yves; Giacchetti, Sylvie; Brain, Etienne; Marty, Michel; Asselain, Bernard; Spyratos, Frederique; Bieche, Ivan, 2018, "COX2/PTGS2 Expression Is Predictive of Response to Neoadjuvant Celecoxib in HER2-negative Breast Cancer Patients", Anticancer Research, vol. 38, no. 3, pp. 1485-1490 DOI:

  • Reyal, F.; Hamy, A. S.; Piccart, Martine J., 2018, "Neoadjuvant treatment: the future of patients with breast cancer", ESMO open, vol. 3, no. 4, pp. e000371 DOI:10.1136/esmoopen-2018-000371

  • Hamy, Anne-Sophie; Lam, Giang-Thanh; Laas, Enora; Darrigues, Lauren; Balezeau, Thomas; Guerin, Julien; Livartowski, Alain; Sadacca, Benjamin; Pierga, Jean-Yves; Vincent-Salomon, Anne; Coussy, Florence; Becette, Veronique; Bonsang-Kitzis, Helene; Rouzier, Roman; Feron, Jean-Guillaume; Benchimol, Gabriel; Lae, Marick; Reyal, Fabien, 2018, "Lymphovascular invasion after neoadjuvant chemotherapy is strongly associated with poor prognosis in breast carcinoma", Breast Cancer Research and Treatment, DOI:10.1007/s10549-017-4610-0

  • Labrosse, Julie; Abdennebi, Ines; Thibault, Lucie; Laas, Enora; Merckelbagh, Hilde; Morel, Charlotte; Lam, Thanh; Lae, Marick; Reyal, Fabien; Hamy, Anne-Sophie, 2018, "Chemosensitivity, tumor infiltrating lymphocytes (TILs), and survival of postpartum PABC patients treated by neoadjuvant chemotherapy", The Breast, DOI:10.1016/j.breast.2018.08.103

    • 2017

  • Sharma, Priyanka; Lopez-Tarruella, Sara; Garcia-Saenz, Jose Angel; Ward, Claire; Connor, Carol S.; Gomez, Henry L.; Prat, Aleix; Moreno, Fernando; Jerez-Gilarranz, Yolanda; Barnadas, Augusti; Picornell, Antoni C.; del Monte-Millan, Maria; Gonzalez-Rivera, Milagros; Massarrah, Tatiana; Pelaez-Lorenzo, Beatriz; Palomero, Maria Isabel; Gonzalez del Val, Ricardo; Cortes, Javier; Fuentes, Hugo; Bretel, Denisse; Marquez-Rodas, Ivan; Perou, Charles M.; Wagner, Jamie L.; Mammen, Joshua V.; McGinness, Marilee K.; Klemp, Jennifer R.; Amin, Amanda L.; Fabian, Carol J.; Heldstab, Jaimie; Godwin, Andrew K.; Jensen, Roy A.; Kimler, Bruce F.; Khan, Qamar J.; Martin, Miguel, 2017, "Efficacy of neoadjuvant carboplatin plus docetaxel in triple negative breast cancer: Combined analysis of two cohorts", Clinical cancer research : an official journal of the American Association for Cancer Research, vol. 23, no. 3, pp. 649-657 DOI:10.1158/1078-0432.CCR-16-0162

  • Hamy, A.-S.; Pierga, J.-Y.; Sabaila, A.; Laas, E.; Bonsang-Kitzis, H.; Laurent, C.; Vincent-Salomon, A.; Cottu, P.; Lerebours, F.; Rouzier, R.; Lae, M.; Reyal, F., 2017, "Stromal lymphocyte infiltration after neoadjuvant chemotherapy is associated with aggressive residual disease and lower disease-free survival in HER2-positive breast cancer", Annals of Oncology: Official Journal of the European Society for Medical Oncology, vol. 28, no. 9, pp. 2233-2240 DOI:10.1093/annonc/mdx309

  • Sadacca, Benjamin; Hamy, Anne-Sophie; Laurent, Cecile; Gestraud, Pierre; Bonsang-Kitzis, Helene; Pinheiro, Alice; Abecassis, Judith; Neuvial, Pierre; Reyal, Fabien, 2017, "New insight for pharmacogenomics studies from the transcriptional analysis of two large-scale cancer cell line panels", Scientific Reports, vol. 7, no. 1, pp. 15126 DOI:10.1038/s41598-017-14770-6

    • 2016

  • Hamy, Anne-Sophie; Bonsang-Kitzis, Helene; Lae, Marick; Moarii, Matahi; Sadacca, Benjamin; Pinheiro, Alice; Galliot, Marion; Abecassis, Judith; Laurent, Cecile; Reyal, Fabien, 2016, "A Stromal Immune Module Correlated with the Response to Neoadjuvant Chemotherapy, Prognosis and Lymphocyte Infiltration in HER2-Positive Breast Carcinoma Is Inversely Correlated with Hormonal Pathways", PloS One, vol. 11, no. 12, pp. e0167397 DOI:10.1371/journal.pone.0167397

  • Bonsang-Kitzis, H.; Sadacca, B.; Hamy-Petit, A. S.; Moarii, M.; Pinheiro, A.; Laurent, C.; Reyal, F., 2016, "Biological network-driven gene selection identifies a stromal immune module as a key determinant of triple-negative breast carcinoma prognosis", Oncoimmunology, vol. 5, no. 1, pp. e1061176 DOI:10.1080/2162402X.2015.1061176

  • Smid, Marcel; Rodriguez-Gonzalez, F. German; Sieuwerts, Anieta M.; Salgado, Roberto; Prager-Van der Smissen, Wendy J. C.; Vlugt-Daane, Michelle van der; van Galen, Anne; Nik-Zainal, Serena; Staaf, Johan; Brinkman, Arie B.; van de Vijver, Marc J.; Richardson, Andrea L.; Fatima, Aquila; Berentsen, Kim; Butler, Adam; Martin, Sancha; Davies, Helen R.; Debets, Reno; Gelder, Marion E. Meijer-Van; van Deurzen, Carolien H. M.; MacGrogan, Gaetan; Van den Eynden, Gert G. G. M.; Purdie, Colin; Thompson, Alastair M.; Caldas, Carlos; Span, Paul N.; Simpson, Peter T.; Lakhani, Sunil R.; Van Laere, Steven; Desmedt, Christine; Ringner, Markus; Tommasi, Stefania; Eyford, Jorunn; Broeks, Annegien; Vincent-Salomon, Anne; Futreal, P. Andrew; Knappskog, Stian; King, Tari; Thomas, Gilles; Viari, Alain; Langerod, Anita; Borresen-Dale, Anne-Lise; Birney, Ewan; Stunnenberg, Hendrik G.; Stratton, Mike; Foekens, John A.; Martens, John W. M., 2016, "Breast cancer genome and transcriptome integration implicates specific mutational signatures with immune cell infiltration", Nature Communications, DOI:10.1038/ncomms12910

  • Gosset, Marie; Hamy, Anne-Sophie; Mallon, Peter; Delomenie, Myriam; Mouttet, Delphine; Pierga, Jean-Yves; Lae, Marick; Fourquet, Alain; Rouzier, Roman; Reyal, Fabien; Feron, Jean-Guillaume, 2016, "Prognostic Impact of Time to Ipsilateral Breast Tumor Recurrence after Breast Conserving Surgery", PloS One, vol. 11, no. 8, pp. e0159888 DOI:10.1371/journal.pone.0159888

    • 2015

  • Hamy-Petit, Anne-Sophie; Belin, Lisa; Bonsang-Kitzis, Helene; Paquet, Caroline; Pierga, Jean-Yves; Lerebours, Florence; Cottu, Paul; Rouzier, Roman; Savignoni, Alexia; Lae, Marick; Reyal, Fabien, 2015, "Pathological complete response and prognosis after neoadjuvant chemotherapy for HER2-positive breast cancers before and after trastuzumab era: results from a real-life cohort", British Journal of Cancer, DOI:10.1038/bjc.2015.426

  • Bonsang-Kitzis, Helene; Chaltier, Leonor; Belin, Lisa; Savignoni, Alexia; Rouzier, Roman; Sablin, Marie-Paule; Lerebours, Florence; Bidard, Francois-Clement; Cottu, Paul; Sastre-Garau, Xavier; Lae, Marick; Pierga, Jean-Yves; Reyal, Fabien, 2015, "Beyond Axillary Lymph Node Metastasis, BMI and Menopausal Status Are Prognostic Determinants for Triple-Negative Breast Cancer Treated by Neoadjuvant Chemotherapy", PloS One, vol. 10, no. 12, pp. e0144359 DOI:10.1371/journal.pone.0144359